“The mineral in our teeth and bones is composed of a highly substituted hydroxyapitite. The substitutions in the mineral crystal lattice disturb the structure and make it much more acid soluble than the pure hydroxyapitite (35). The primary major substitution is carbonate that replaces some of the phosphate leading to an acid soluble mineral (38, 39).”

John Featherstone et al., 2001, Fundamental Interactions of Lasers with Dental Hard Tissues, https://doi.org/10.1078/1615-1615-00022

“In addition, the combination of CO2 laser irradiation with fluoride dentifrice use provided significantly more protection against demineralization than did laser irradiation or fluoride dentifrice use alone.”

John Featherstone et al., 2006, In Situ Mineral Loss Inhibition by CO2 Laser and Fluoride, https://doi.org/10.1177/154405910608500707

“All of the laser irradiation conditions tested in this study produced statistically significant inhibition of subsequent caries-like lesion formation with a total irradiation time of only 2.5 s (2.5 ms of actual laser irradiation). Inhibition of caries progression of from 40% to 85% was achieved, whereas in our previous studies (Nelson et al., 1986, 1987), we were able to achieve a maximum of only 50% inhibition, with most conditions giving only 10 to 40’%.”

John Featherstone et al., 1998, CO2 Laser Inhibition of Artificial Caries-like Lesion Progression in Dental Enamel, https://doi.org/10.1177/00220345980770060401